Publications

 

For  complete updated list of total number of refereed journal publications click here

 

 

 

 

1.1 Partial list of Refereed Journal Publications. Total today: 177 refereed journal publications.

 

1.             Buescher, J.M. and Margaritis, A. (2007) “Microbial Biosynthesis of Polyglutamic Acid Biopolymer and Applications in the Biopharmaceutical, Biomedical and Food Industries”, Crit. Rev. Biotechnol., 27 (1): 1-19.

 

2.             Jones, H., Margaritis, A. and Stewart, R.J., (2007), “The Combined Effect of Oxygen Supply Strategy, Inoculum Size and Temperature Profile on Very-High-Gravity- Beer Fermentation by Saccharomyces Cerevisiae”, Journal of Institute of Brewing, 113 (2): 168-187.

 

3.             Kilonzo, P., Margaritis, A., Yu, J.T. and Q. Ye, (2007), “Bioethanol Production from Starchy Biomass by Direct Fermentation using Saccharomyces diastaticus in Batch Free and Immobilized Cell Systems”, International Journal of Green Energy, 4: 1-14.

 

4.             Kilonzo, P., Margaritis, A., Yu, J.T. and Q. Ye, (2007), “Effects of Geometrical Design on Hydrodynamics and Mass Transfer Characteristics of a Rectangular Column Airlift Bioreactor”, Biochemical Engineering Journal, 34(3): 279-288.

 

5.             Ly, M., Margaritis, A., and B. Jajuee, (2007), “Effects of Solvent Concentration on the Extraction Kinetcics and Diffusivity of Cyclosporin A in the Fungus Tolypocladium inflatum”, Biotechnology and Bioengineering, 96 (1): 67-79.

 

6.             Ly, M., Margaritis, A., (2007), “Effect of Temperature on the Extraction Kinetics and Diffusivity of Cyclosporin A in the Fungus Tolypocladium inflatum”, Biotechnology and Bioengineering, 96 (5): 945-955.

 

7.             Jajuee, B., Margaritis, A., Karamanev, D., and M.A. Bergougnou, (2007), “Kinetics of Biodegradation of p-Xylene and Naphthalene and Oxygen Transfer in a Novel Airlift Immobilized Bioreactor” Biotechnology and Bioengineering, 96 (2): 232-243.

 

8.             Soleimani, M., Bassi, A., and A. Margaritis (2007), “Biodesulfurization of Refractory Organic Sulfur Compounds in fossil Fuels”, Biotechnology Advances, 25(6): 570-596.

 

9.             Manocha, B., and A. Margaritis (2007), “Poly-Glutamic Acid Nanoparticles Production and Characterization for Controlled Drug Release”, Adv. Drug Deliv. Rev. (submitted).

 

10.         Kilonzo, P., Margaritis, A., Bergougnou, M.A., Yu, J.T.,  and Q. Ye, (2006), “Influence of Baffle Clearance Design on Hydrodynamics of a Two Riser rectangular Airlift Reactor with Inverse Internal Loop and Expanded Gas-Liquid Separator”, Chemical Engineering Journal, 121 (1): 17-26.

 

11.         Kermanshahipour, A., Karamanev, D., and A. Margaritis, (2006) “Kinetic modeling of the biodegrdation of the aqueous p-xylene in the immobilized soil bioreactor”, Biochemical Engineering Journal, 27: 204-211.

 

12.         Richard, A. and A. Margaritis, (2006) “Kinetics of molecular weight reduction of poly(glutamic acid) by in situ depolymerization in cell-free broth of Bacillus subtilis” Biochemical Engineering Journal, 30: 303-307.

 

13.         Jajuee, B., Margaritis, A., Karamanev, D., and M.A. Bergougnou, (2006), “Application of Surface-Renewal-Stretch Model for Interface Mass Transfer”, Chemical Engineering Science, 61: 3917-3929.

 

14.         Jajuee, B., Margaritis, A., Karamanev, D., and  M.A. Bergougnou, (2006), “Influence of Dissolved Hydrocarbons on Volumetric Mass Transfer Coefficient in a Novel Airlift Contactor” Chemical Engineering Science, 61: 4111-4119.

 

15.         Jajuee, B., Margaritis, A., Karamanev, D., and M.A.Bergougnou, (2006), “Mass Transfer Characteristics of a Novel Three-phase Airlift Contactor with a Semipermeable membrane”, Chemical Engineering Journal, 125: 119-126.

 

16.         Jajuee, B., Margaritis, A., Karamanev, D., and  M.A. Bergougnou, (2006), “Measurements and CFD Simulations of Gas Holdup and liquid velocity in novel Airlift Membrane Contactor”, AIChE Journal, 52(12): 4079-4089.

 

17.         Margaritis, A., and P. Kilonzo, “Production of Ethanol Using Immobilized Cell Bioreactor Systems” (2005) in: “Applications of Cell Immobilization Technology” V. Nedovic and R. Willaert (Eds.), Springer, Dordrecht, The  Netherlands, pp.375- 405

 

18.         Kermanshahipour, A., Karamanev, D., and A. Margaritis, (2005), “Biodegradation of petroleum hydrocarbons in an immobilized cell bioreactor”, Water Research, 39: 3704-3714.

 

19.         Patel, J., Nakhla, G., and A Margaritis, (2005), “Optimization of biological nutrient removal in a membrane bioreactor system”, Journal of Environmental Engineering, 131(7): 1021-1029.

 

20.         Barfett, J., Lanting, B., Margaritis, A., Herbert, C., and J. Silcox  (2005), “Integrated Medical and Engineering Undergraduate Training”, Letters Correspondence: Canadian Medical Association Journal, 172: 1537.

 

21.         Karamanev, D., Deswbury, K., Margaritis, A., (2005), “Comments on the Free Rise of Gas Bubbles in non-Newtonian Liquids”, Letter to the Editor: Chemical Engineering Science, 60: 4655-4657.

 

22.         Rowe G.E. and Margaritis, A., (2004), “Enzyme Kinetic Properties of 4-Glucosidase in Bacillus thuringiensis”, Biochemical Engineering Journal, 17: 121-128.

 

23.         Rowe G.E. and Margaritis, A., (2004), “Bioprocess Design and Economic Analysis for the Commercial Production of Environmentally Friendly Bioinsectcides from Bacillus thuringiensis HD-1 kurstaki”, Biotechnology and Bioengineering, 86(4): 377-388.

 

24.         Petersen, E., Margaritis A., Stewart, R.J., Pilkington, P.H., Mensour, N.A., (2004), “The Effects of Wort Valine Concentration on the Total Diacetyl Profile and Levels Late in Batch Fermentations with Brewing Yeast Saccharomyces carlsbergensis”, American Society Brewing Chemists Journal, 62(4): 131-139.

 

25.         Kilonzo, P. and A. Margaritis, (2004), “The Effects of non-Newtonian Fermentation Broth Viscosity and Small Bubble Segregation on Oxygen Mass Transfer in Air-Lift Bioreactors”, Biochemical Engineering Journal, 17 (1): 27-40.

 

26.         Richard, A. and A. Margaritis, (2004), “Empirical Modeling of Batch Fermentation Kinetics for Poly (glutamic acid) Production and Other Microbial  Biopolymers”, Biotechnology and Bioengineering, 84(4): 501-515.

 

27.         Tzounakos, A., Karamanev, D.G., Margaritis, A., and M.A. Bergougnou, (2004), “Effect of Surfactants on the Free Rise of Single Gas Bubbles in Non-Newtonian Pseudoplastic Liquids”, Ind. Eng. Chem. Research, 43: 5790-5795.

 

28.         Puskas, J.E., Dahman, Y., and A. Margaritis, (2004) “Novel Thymine – Functionalized Polystyrenes for Applications in Biotechnology. Adsorption of Model Proteins” Biomacromolecules, 5: 1412-1421.

 

29.         Barghi, S.,  Prakash, A., Margaritis, A., and M.A. Bergougnou, (2004), “Flow regime identification in a slurry bubble column from gas holdup and pressure fluctuation analysis” Canadian Journal of Chemical Engineering, 82: 865-870.

 

30.         Joseph, G., Rowe, G.E., Margaritis, A., and W.K. Wan, (2003), “Effects of Polyacrylamide-co-Acrylic Acid on Cellulose Production by Acetobacter xylinum”, Journ. Chem. Tech. Biotech., 78(9): 964-970.

 

31.         Dahman, Y., Puskas, J.E., Margaritis, A., Merali, Z. and M. Cunningham, (2003), “Novel Thymine-Functionalized Polystyrenes for Applications in Biotechnology, Polymer Synthesis and Characterization”, Macromolecules, 36 (7): 2198-2205.

 

32.         Rowe, G.E., Margaritis, A., and N. Wei, (2003), “Specific Oxygen Uptake Rate Variations During Batch Fermentation of B. thuringiensis, kurstaki HD-1”, Biotechnology Progress, 19(5): 1439-1443.

 

33.         Richard, A., and Margaritis, A., (2003), “Optimization of Cell Growth and Poly (glutamic acid) Production in Batch Fermentation by Bacillus subtillis”, Biotechnology Letters, 25(6): 465-468.

 

34.         Richard, A., and Margaritis, A, (2003), “Rheology, Oxygen Transfer and Mol. Weight Characteristics of Poly (glutamic acid) Fermentation by Bacillus subtilis”,   Biotechnology and Bioengineering, 82(3): 299-305.

 

35.         Lan, Q., Bassi, A.S., Zhu, J-X, and  Margaritis, A, (2002), “Continuous Protein Recovery from Whey using Liquid-Solid Circulating Fluidized Bed Ion- Exchange Extraction”, Biotechnology and Bioengineering, 78(2): 157-163.

 

36.         Lan, Q., Bassi, A.S., Zhu, J-X, and Margaritis, A., (2002), “Continuous Protein Recovery with Liquid-Solid Circulating Fluidized-Bed Ion Exchanger”, AIChE Journal, 48(2): 252-261.

 

37.         Dewsbury, K.H., Tzounakos, A., Karamanev, D.G., and Margaritis, A., (2002), “Wall Effects for Free Rise of Solid Spheres in Moderately Viscous Liquids”, Canadian Journal of  Chemical Engineering, 80(5): 974-978.

 

38.         Dewsbury, K.H., Karamanev, D.G., and Margaritis, A., (2002), “Rising Solid Sphere Hydrodynamics at High Reynolds Numbers in Non-Newtonian Fluids”, Chemical Engineering Journal, 87(1): 129-133.

 

39.         Chong, N., Karamanev, D.G., and Margaritis, A., (2002), “Effect of Particle-Particle Shearing on the Bioleaching of Sulfide Minerals”, Biotechnology and Bioengineering, 80(3): 349-357.

 

40.         Richard, A. and Margaritis, A., (2002),“Production and Mass Transfer Characteristics of Non-Newtonian Biopolymers for Biomedical Applications”, Critical Reviews in Biotechnology., 22(4): 355-374.

 

41.         Dahman, Y., Puskas, J.E., Margaritis, A., Marali, A., Cunningham, M., (2002), “Synthesis and Characterization of Functionalized Polystyrene”, Polymer Preprints, American Chemical Society, Division of Polymer Chemistry, 43(1): 262-265.

 

42.         Prakash, A., Margaritis*, A., Li, H., and Bergougnou, M.A., (2001),  “Hydrodynamics and Local Heat Transfer Measurements in a Bubble Column with Suspension of Yeast”, Biochemical Engineering Journal, 9(2): 155-163.

 

43.         Peterson, E., and Margaritis*, A., (2001), “Hydrodynamic and Mass Transfer Characteristics of Three-Phrase Gas-Lift Bioreactor Systems”, C.R.C. Crit. Rev. Biotechnology, 21(4): 233-294.

 

44.         Richard, A., and Margaritis*, A., (2001), “Poly(glutamic acid) for Biomedical Applications”, C.R.C. Crit. Rev. Biotechnology, 21(4): 219-232.

 

45.         Karamanev, D., Margaritis, A., and N. Chong, (2001), “The Application of Ore   Immobilization to the Bioleaching of Gold Concentrate”, Intl. Journ. Mineral Processing, 62: 231-241.

 

46.         Lan, Q., Bassi, A.S. , Zhu, J-X. and Margaritis, A., (2001), “A Modified Langmuir Model for the Prediction and the Effects of Ionic Strength on the Equilibrium Characteristics  of Protein Adsorption onto Ion Exchange/Affinity Adsorbents”, Chemical  Engineering Journal, 81(1): 179-186.

 

47.         Heggart, H.M., Margaritis, A., Stewart, R.J., Pilkington, H., Sobczak, J. and I. Russell, (2000), “Measurement of Brewing Yeast Viability and Vitality”, Technical Quarterly, Master Brewers Association of the Americas, 37(4): 409-430.

 

48.         Bassi, A., Ding, D.N. , Gloor, G. and. Margaritis, A., (2000), “Expression of Single Chain Anitibodies for C-Myc Oncoprotein in Recombinant E. coli Membranes by Using the Ice-Nucleation Protein of Pseudomonas Syringae”, Biotechnology Progress, 16: 557-563.

 

1.2 Technical Research Reports. Total today: 13

 

49.Prakash, A., Margaritis, A., and A. Tyagi, (1998), “Design and Development of Agitated Slurry Reactor for Absorption of 14-CO₂ in Lime Slurry”, Final report, Atomic Energy Can. Ltd., 47 pages.

 

50.Margaritis, A., (2003), “Development of Non-Toxic Biodegradable Bioinsecticides”, Final 3-Year report submitted to the EJLB Foundation, Montreal, Quebec, 55 pages.

 

1.3 Patents Pending Total today: 10

 

1.     Margaritis, A. and P.S. Chahal, “Flurosensor-Controlled Fed-Batch Production of Cyclosporine”. Filed to Canadian Patent Office, October 1993.

2.     Margaritis, A., and D.W. te Bokkel and G.E. McElroy, “Supercritical Carbon Dioxide Extraction of Cyclosporin”. Filed to Canadian Patent Office, October 1993.

3.     Margaritis, A., L.W. Jiang and N.O. Petersen, “Opticial Fiber Epifluorescence Biosensor”. Filed to Canadian Patent Office. March 1993.

4.     Margaritis, A. and P.A. Paprica and N.O. Petersen, “Cyclosporin Derivatives and Derivative Conjugates”. Filed to Canadian Patent Office, December 1992, also filed to U.S. Patent Office, December 1992.

5.     Bassi, A., Zhu, J-X, Lan, Q., Margaritis, A., and Y. Zheng, “Continuous Ion Exchange Using a Liquid-Solid Circulating Fluidized Bed”, U.S. Patent No. 6,716,344, April 6, 2004.

6.     Bassi, A., Zhu, J-X., Lan, Q., Margaritis, A., and Y. Zheng, “Method for Recovering Products Using Liquid-Solids Circulating Fluidized Bed”, filed to U.S. Patent Office, Serial No. 09/676,453, Feb. 19, 2004.

7.     Karamanev, D., and A. Margaritis, “Immobilized Bioreactor Method for Sulphidic Minerals and Other Particulate Solids”, U.S. Patent: 6, 214,088 B1, April 10, 2001.

8.     Karamanev, D., and A. Margaritis, “Immobilized Bioreactor Method for Sulphidic Minerals and Other Particulate Solids”, Can. Patent Office, No. 2,314,803, Aug. 1, 2000.

9.     Petersen, E., Margaritis, A., Stewart, R., Pilkington, P.H., McGarrity, M.J., Mensour, N. Forster,C., and J.A. Sobczak, “Methods, Processes and Wort Compositions Related to Vicinal Diketone Evolution and Especially Diacetyl Formation in Brewing”, U.S. Patent Application no. 10/270, 240, Oct. 28, 2002.

10.   Petersen, E., Margaritis, A., Stewart, R., Pilkington, P.H., McGarrity, M.J., Mensour, N. Forster,C., and J.A. Sobczak, “Methods, Processes and Wort Compositions Related to Vicinal Diketone Evolution and Especially Diacetyl Formation in Brewing”, Can. Patent Office, No. 2,463,335, filed: Oct.11, 2002.

 

1.4 Papers in Refereed Proceedings. Total today: 19

 

1.5 Papers Presented at Scientific Conferences. Total today: 187

 

1.6 Other Contributions:

 

1. Chairman, P.E.O., London Chapter

2. Consulting several biotechnology companies.

3. Referee for 16 different international scientific journals.

4. Established the first Biosensors Research Group at U.W.O.

5. Chairman, Dept. of Chem. & Biochem. Eng., UWO.

6. Founding Director, London District, Aventis Biotech. Challenge, which selects annually the best high school students interested in biotechnology.

7. Senator, U.W.O. Senate.

8. Chairman, Bioengineering Task Force Committee, Professional Engineers Ontario, Toronto, report approved by the PEO Council.

9. President and CEO, Biomar Inc.

10. Member, Selection Committee, Dean of Engineering, U.W.O.

11. Member, Faculty Council representative, Ivey Business School, U.W.O.

12. Member, Bioinformatics Western, U.W.O.

13. Member, Promotion and Tenure Committee Faculty of Science, U.W.O.